Reduction in all the cell lines of blood the values of the 3 components being. Definition combination of anemia, leucopenia and thrombocytopenia hb pancytopenia can be associated with a multitude of disease states, some of which are life threatening. Its combination of anemia, leukopenia and thrombocytopenia 1. This blood cell disorder is seen in many hematological diseases, especially in megaloblastic anemia. Pancytopenia is a disorder associated with decrease in number. Clinical presentation of the patients with pancytopenia. Aplastic anemia market revenueken research aplastic anemia is a syndrome of bone marrow failure characterized by peripheral pancytopenia and marrow hypoplasia. The term cytopenia reduction in either of the cellular component of blood pancytopenia. A through approach to pancytopenia slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising.
Assessment of pancytopenia differential diagnosis of. To study the clinical presentations in pancytopenia due to various causes. Data sources include ibm watson micromedex updated 10 apr 2020, cerner multum updated 6 apr 2020, wolters kluwer updated. View and download powerpoint presentations on approach to pancytopenia ppt.
Hb pancytopenia was diagnosed in the presence of anemia hematocrit value powerpoint presentation last. A thoughtful history and physical examination along with focused laboratory studies are required to establish a diagnosis and select proper management. Pancytopenia is an important clinicohematological entity encountered in our daytoday clinical practice. Find powerpoint presentations and slides using the power of, find free presentations research about approach to pancytopenia ppt. Pancytopenia is a reduction in the number of rbcs, wbcs and, platelets in the peripheral blood below the lower limits of the ageadjusted normal range for healthy people.
Symptoms include fatigue, pale skin, rapid or irregular heart rate, shortness of breath with exertion, nosebleeds and bleeding gums, prolonged bleeding from cuts, skin rash, dizziness and headache. Two patients presented with pancytopenia due to two different causes. It was mainly due to use of toxic and bandrugs by quacks and. Pancytopenia develops due to vitamin deficiencies, hematologic, gastrointestinal, endocrine diseases, and infections.
There are varying trends in its clinical pattern, treatment modalities, and outcome. The first was a patient of druginduced pancytopenia who ultimately had good recovery. On conclusion, aplastic anemia was the most common cause of pancytopenia in our study predominantly affecting young adult males. Definition the simultaneous presence of anemia leukopenia thrombocytopenia hb pancytopenia haemoglobin of pancytopenia absolute neutrophil count pancytopenia was aplastic anemia noted in 3035. Ataxiapancytopenia syndrome is a rare condition that affects the part of the brain that coordinates movement the cerebellum and bloodforming cells in the bone marrow. Pancytopenia is defined as lack of all types of blood cells. Platelets stop the bleeding when you are cut or injured. Pancytopenia is low levels of red blood cells, white blood cells, and platelets. Aplastic anemia is also a hematological disease characterized by bone marrow hypoplasia and pancytopenia 1. White blood cells help your body fight infection by attacking and killing germs. Approach to pancytopenia moderator dr vishal gupta md medicine. Pancytopenia welcome to association of physicians of india. Subjects with aplastic anemia present with varying combinations of symptomatic anemia, bleeding, and infection, depending upon the severity of the pancytopenia.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Overall, the most common cause of pancytopenia was aplastic anemia noted in 3035. Etiological causes of pancytopenia were categorized as four main groups, including hematological diseases in 94 patients 37. Pancytopenia definition of pancytopenia by merriamwebster. Ataxiapancytopenia syndrome genetics home reference nih. Pancytopenia haemoglobin of pathogenesis and diagnosis of aplastic anaemia sameer r melinkeri consultant haematologist, deenanath mangeshkar hospital, pune, maharashtra epidemiology the incidence of aplastic anaemia shows geographical variability. Pancytopenia is a reduction in the number of red blood cells, white blood cells, and platelets in the peripheral blood below the lower limits of the ageadjusted normal range for healthy people. Red blood cells carry oxygen to all the organs and tissues of your body.